DPP4抑制劑篩選試劑盒說明書
產(chǎn)品名稱：DPP4抑制劑篩選試劑盒
英文名稱：DPP4 Inhibitor Screening Kit
貨號：K780-100
分類：原裝進口
規(guī)格：100T
英文簡介：
Dipeptidyl peptidase-4 (DPP4) inhibitors have emerged as a new class of oral antidiabetic agents. These inhibitors promote glucose homeostasis by inhibiting degradation of glucosedependent insulinotropic polypeptide and glucagon-like peptide-1 by DPP4. Glucagon-like peptide-1 extends the action of insulin while suppressing the release of glucagon. In BioVision’s DPP4 Inhibitor Screening Kit, DPP4 cleaves a substrate to release a quenched fluorescent group (Ex/Em = 360/460 nm). In presence of a DPP4 inhibitor, the cleavage will be inhibited.The kit provides a rapid, simple, sensitive, and reliable test, as well as, suitable for high throughput screening of DPP4 inhibitors. Sitagliptin is included as a control inhibitor to compare
the efficacy of the test inhibitors.
試劑盒中文簡介: DPP4抑制劑篩選試劑盒中，DPP4能切割底物釋放淬滅的熒光集團（Em/Ex = 360/460 nm）.如果存在抑制劑，切割將被抑制.本試劑盒快速，簡單，靈敏實驗結(jié)果可靠，并能適應(yīng)于高通量活性篩選DPP4抑制劑.試劑盒含有西他列汀作為對照來檢測抑制劑的功效.
產(chǎn)品背景: 二肽基肽酶-4（DPP4）抑制劑已成一種新型口服抗糖尿病藥物.這些抑制劑可以促進葡萄糖體內(nèi)平衡，通過抑制Dpp4 降解葡糖依賴的促胰島素多肽和胰高血糖素樣肽1..胰高血糖樣肽1能增加胰島素的活性抑制胰高血糖素的釋放.
產(chǎn)品特點: 1、簡單操作，實驗僅需要30分鐘；2、方便快捷；3、靈敏可靠地高通量試驗
保存建議：請在接收到DPP4抑制劑篩選試劑盒產(chǎn)品后，置于-20℃保存.
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